A study in The Journal of Clinical Endocrinology & Metabolism found that moderate coffee or caffeine intake was associated with a lower risk of developing cardiovascular disease. Researchers in China and Sweden analyzed the consumption habits of more than 188,000 coffee and tea drinkers in the U.K. Biobank, a large database of genetic, health and lifestyle information from half a million participants accumulated since 2006.

None of the participants in the study were diagnosed with cardiometabolic disease, a disease defined as having at least two of three conditions—Type 2 diabetes, coronary heart disease or stroke. After tracking these participants for 12 years, the researchers found that those consuming 200 to 300 milligrams of caffeine daily had a lower risk of cardiometabolic disease than those consuming less than 100 milligrams. Coffee drinkers had a nearly 50 percent reduction in risk. A 12-ounce cup of coffee contains 100 to 180 milligrams of caffeine.